The HSPB7 Polyclonal Antibody (CAB18450) is a valuable tool for researchers studying heat shock protein beta-7 (HSPB7), a protein involved in protecting cells from stress-induced damage. This rabbit polyclonal antibody is highly specific for detecting HSPB7 in human samples and is validated for use in Western blot applications. By binding to HSPB7, this antibody allows for precise detection and analysis of the protein in various cell types, making it an ideal choice for studies in molecular biology and cellular stress response.HSPB7 is a member of the small heat shock protein family and is known for its role in maintaining cell homeostasis under conditions of stress, such as heat or oxidative stress.
Research on HSPB7 is important for understanding the mechanisms that cells use to protect themselves from damage and for developing therapies that target cell stress responses in diseases like cardiovascular disorders, neurodegenerative conditions, and metabolic disorders. This antibody provides a reliable tool for investigating the function and regulation of HSPB7 in these contexts.
Product Name:
HSPB7 Rabbit Polyclonal Antibody
SKU:
CAB18450
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-170 of human HSPB7 (NP_055239.1).
This gene encodes a small heat shock family B member that can heterodimerize with similar heat shock proteins. Defects in this gene are associated with advanced heart failure. In addition, the encoded protein may be a tumor suppressor in the p53 pathway, with defects in this gene being associated with renal cell carcinoma.
Purification Method:
Affinity purification
Gene ID:
27129
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HSPB7 Rabbit pAb (CAB18450) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
