The HSPA9 Polyclonal Antibody (CAB0558) is a valuable tool for researchers studying the HSPA9 protein, also known as mortalin. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the HSPA9 protein, researchers can detect and analyze its expression in various cell types, providing insights into its role in cellular function and disease processes.HSPA9 is a crucial molecular chaperone involved in protein folding, transport, and quality control within the cell. Its functions extend beyond basic housekeeping tasks, as it has been implicated in regulating cell proliferation, apoptosis, and stress response pathways.
Dysregulation of HSPA9 has been linked to various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.By using the HSPA9 Polyclonal Antibody, researchers can delve into the intricate mechanisms by which HSPA9 influences cellular processes and disease pathogenesis. This antibody is an essential tool for studies in molecular biology, cell biology, and disease research, with the potential to uncover novel therapeutic targets and diagnostic markers associated with HSPA9 function.
Product Name:
Grp75/MOT/HSPA9 Rabbit Polyclonal Antibody
SKU:
CAB0558
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 380-679 of human Grp75/MOT/Grp75/MOT/HSPA9 (NP_004125.3).
This gene encodes a member of the heat shock protein 70 gene family. The encoded protein is primarily localized to the mitochondria but is also found in the endoplasmic reticulum, plasma membrane and cytoplasmic vesicles. This protein is a heat-shock cognate protein. This protein plays a role in cell proliferation, stress response and maintenance of the mitochondria. A pseudogene of this gene is found on chromosome 2.
Purification Method:
Affinity purification
Gene ID:
3313
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Grp75/MOT/HSPA9 Rabbit pAb (CAB0558) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
