The HSPA8 Polyclonal Antibody (CAB2487) is a valuable tool for researchers studying the heat shock protein HSPA8, also known as Hsc70. This antibody, developed through rabbit immunization, exhibits high specificity and sensitivity in detecting HSPA8 in human samples, making it ideal for Western blot applications.HSPA8 is a crucial chaperone protein involved in regulating cellular stress responses and protein folding. Its role in maintaining protein homeostasis and cell survival makes it a key player in various cellular processes, including the immune response and cancer development.
The HSPA8 Polyclonal Antibody enables researchers to investigate the expression and function of HSPA8 in different cell types, providing insights into its involvement in disease pathways.By studying HSPA8 using this antibody, researchers can gain a better understanding of its mechanisms of action and potential implications in diseases such as cancer, neurodegenerative disorders, and metabolic conditions. The HSPA8 Polyclonal Antibody is a valuable tool for advancing research in molecular biology, cell biology, and biomedical sciences.
Product Name:
Hsc70/HSPA8 Rabbit Polyclonal Antibody
SKU:
CAB2487
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat,Monkey
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 510-615 of human Hsc70/HSPA8 (NP_006588.1).
Sequence:
LSKE DIER MVQE AEKY KAED EKQR DKVS SKNS LESY AFNM KATV EDEK LQGK INDE DKQK ILDK CNEI INWL DKNQ TAEK EEFE HQQK ELEK VCNP IITK LYQS AG
This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3312
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using (CAB2487) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
