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HSPA5 Monoclonal Antibody [PAT3D2AT] (CPAB0291)

SKU:
CPAB0291
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
PAT3D2AT
Applications:
WB
ELISA
€149
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Description

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HSPA5 Monoclonal Antibody [PAT3D2AT] (CPAB0291)

The HSPA5 Polyclonal Antibody (CPAB0291) is a valuable tool for researchers studying heat shock protein A5 (HSPA5), also known as Grp78. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it an ideal choice for Western blot applications.HSPA5 is a key molecular chaperone involved in protein folding and quality control in the endoplasmic reticulum. It plays a crucial role in regulating cellular stress responses, particularly in conditions such as cancer, neurodegenerative diseases, and cardiovascular disorders. By targeting HSPA5 with this antibody, researchers can investigate the role of this protein in disease pathogenesis and potential therapeutic strategies.

With its high specificity and reactivity, the HSPA5 Polyclonal Antibody (CPAB0291) offers a reliable tool for researchers interested in unraveling the complex functions of HSPA5 in various cellular processes and disease states. By accurately detecting and analyzing HSPA5 expression in different cell types, this antibody is a valuable asset for studies in molecular biology, cell biology, and biomedical research.

Product Name:HSPA5 Antibody
Product Sku:CPAB0291
Size:5μg
Host Species:Mouse
Immunogen:Anti-human HSPA5 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human HSPA5 protein 2-65 amino acids purified from Baculovirus.
Clone:PAT3D2AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:HSPA5 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG1
Background:Binding immunoglobulin protein (BiP or HSPA5) is a member of the family of ~70kDa heat shock proteins (HSP 70). HSPA5 is a stress response protein which is induced by agents or conditions that adversely affect endoplasmic reticulum (ER) function. HSPA5 is crucial for the proper glycosylation, folding as well as for the maintenance of cell homeostasis and the prevention of apoptosis.
Synonyms:78 kDa glucose-regulated protein, GRP-78, Endoplasmic reticulum lumenal Ca(2+)-binding protein grp78, Heat shock 70 kDa protein 5, Immunoglobulin heavy chain-binding protein, BiP, HSPA5, GRP78, MIF2, FLJ26106.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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