The HSPA4L Polyclonal Antibody (CAB17637) is a valuable tool for researchers studying the HSPA4L protein, a member of the heat shock protein family involved in cellular stress response. This rabbit polyclonal antibody is highly specific for human samples and has been validated for use in Western blot applications.HSPA4L, also known as heat shock 70 kDa protein 4-like, plays a crucial role in maintaining protein homeostasis under stress conditions. Its function in protein folding and quality control makes it essential for cellular survival and function. Research into HSPA4L can provide insights into mechanisms of cell survival and potential therapeutic targets for diseases related to protein misfolding.
By using the HSPA4L Polyclonal Antibody, researchers can accurately detect and analyze the expression of HSPA4L in various cell types, facilitating studies in cellular stress responses, protein quality control, and related pathways. Understanding the role of HSPA4L in cellular homeostasis is vital for advancing knowledge in cell biology and the development of novel therapeutic strategies targeting protein misfolding disorders.
Product Name:
HSPA4L Rabbit Polyclonal Antibody
SKU:
CAB17637
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 500-600 of human HSPA4L (NP_055093.2).
The protein encoded by this gene is heat shock inducible and may act as a chaperone. The encoded protein can protect the heat-shocked cell against the harmful effects of aggregated proteins. This gene is highly expressed in leukemia cells and may be a good target for therapeutic intervention. Several transcripts encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
22824
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HSPA4L Rabbit pAb (CAB17637) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
