HSPA1L/HSPA1A Antibody (PACO06564)
- SKU:
- PACO06564
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- IHC
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
HSPA1L/HSPA1A Antibody (PACO06564)
The HSPA1L/HSPA1A Antibody (PACO06564) is a highly specific and sensitive tool for studying the heat shock proteins HSPA1L and HSPA1A. These proteins are members of the HSP70 family, playing essential roles in cellular stress response and protein folding. The antibody, derived from rabbit hosts, exhibits strong reactivity with human samples and is validated for use in applications such as Western blotting.Through binding to HSPA1L and HSPA1A proteins, this antibody enables precise detection and analysis in various cell types, making it ideal for research in fields such as molecular biology, cell biology, and biochemistry.
Understanding the functions and regulation of these heat shock proteins is crucial for unraveling their involvement in physiological processes and diseases such as cancer, neurodegeneration, and cardiovascular disorders.By utilizing the HSPA1L/HSPA1A Antibody (PACO06564), researchers can gain valuable insights into the intricate mechanisms underlying cellular stress responses and protein quality control, paving the way for the development of targeted therapies and interventions to combat stress-related disorders.
| Antibody Name: | HSPA1L/HSPA1A Antibody (PACO06564) |
| Antibody SKU: | PACO06564 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB, IHC |
| Recommended Dilutions: | ELISA:1:40000, WB:1:500-1:2000, IHC:1:100-1:300 |
| Species Reactivity: | Human, Mouse, Rat |
| Immunogen: | Synthesized peptide derived from the Internal region of human HSP70. |
| Form: | Liquid |
| Storage Buffer: | Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide. |
| Purification Method: | The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western Blot analysis of various cells using HSP70 Polyclonal Antibody. |
 | Western Blot analysis of MCF-7 cells using HSP70 Polyclonal Antibody. |
| Synonyms: | HSPA1L; Heat shock 70 kDa protein 1-like; Heat shock 70 kDa protein 1L; Heat shock 70 kDa protein 1-Hom; HSP70-Hom; HSPA1A; HSPA1; HSPA1B; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2 |
| UniProt Protein Function: | HSPA1L: In cooperation with other chaperones, Hsp70s stabilize preexistent proteins against aggregation and mediate the folding of newly translated polypeptides in the cytosol as well as within organelles. These chaperones participate in all these processes through their ability to recognize nonnative conformations of other proteins. They bind extended peptide segments with a net hydrophobic character exposed by polypeptides during translation and membrane translocation, or following stress-induced damage. Not induced by heat shock. Expressed in spermatids. Belongs to the heat shock protein 70 family. |
| UniProt Protein Details: | Protein type:Heat shock protein; Mitochondrial; Chaperone Chromosomal Location of Human Ortholog: 6p21.3 Cellular Component: signalosome; nucleoplasm; mitochondrial matrix; cytosol Molecular Function:protein binding; unfolded protein binding; ATP binding Biological Process: binding of sperm to zona pellucida; protein refolding; response to unfolded protein |
| NCBI Summary: | This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which also encode isoforms of the 70kDa heat shock protein. [provided by RefSeq, Jul 2008] |
| UniProt Code: | P34931 |
| NCBI GenInfo Identifier: | 23831140 |
| NCBI Gene ID: | 3305 |
| NCBI Accession: | P34931.2 |
| UniProt Secondary Accession: | P34931,O75634, Q2HXR3, Q8NE72, Q96QC9, Q9UQM1, A6NNB0 B0UXW8, |
| UniProt Related Accession: | P34931 |
| Molecular Weight: | 641 |
| NCBI Full Name: | Heat shock 70 kDa protein 1-like |
| NCBI Synonym Full Names: | heat shock 70kDa protein 1-like |
| NCBI Official Symbol: | HSPA1LÂ Â |
| NCBI Official Synonym Symbols: | HSP70T; hum70t; HSP70-1L; HSP70-HOMÂ Â |
| NCBI Protein Information: | heat shock 70 kDa protein 1-like; heat shock 70 kDa protein 1L; heat shock 70kD protein-like 1; heat shock 10kDa protein 1-like; heat shock 70 kDa protein 1-Hom |
| UniProt Protein Name: | Heat shock 70 kDa protein 1-like |
| UniProt Synonym Protein Names: | Heat shock 70 kDa protein 1-Hom; HSP70-Hom |
| Protein Family: | Heat shock 70 kDa protein |
| UniProt Gene Name: | HSPA1LÂ Â |
| UniProt Entry Name: | HS71L_HUMAN |
Related Products
HSPA1A Antibody (PACO09824)
HSPA1A Antibody (PACO07255)
HSPA1A Antibody (PACO02105)
HSPA1A Polyclonal Antibody (CAB20819)
Anti-HSPA1L Antibody (MACO0016)
Acetyl-HSPA1A (K246) Antibody (PACO06085)
