The HSPA1A Polyclonal Antibody (PACO09824) is a valuable tool for researchers studying the HSPA1A protein, a member of the heat shock protein family that plays a crucial role in cellular stress response and protein folding. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.HSPA1A, also known as heat shock 70kDa protein 1A, is involved in protecting cells from stress-induced damage and promoting proper folding of proteins to maintain cellular homeostasis. Its function in stress response pathways makes it a key player in various physiological and pathological processes, including cancer, neurodegenerative diseases, and metabolic disorders.
By targeting the HSPA1A protein, researchers can gain insights into its role in cellular stress response mechanisms and its potential as a therapeutic target for diseases characterized by protein misfolding or oxidative stress. The HSPA1A Polyclonal Antibody (PACO09824) enables accurate detection and analysis of HSPA1A expression in different cell types, making it a valuable tool for studies in cell biology, cancer research, and therapeutic development.
heat shock 70kDa protein 1A;HSPA1A;FLJ54303;FLJ54370;FLJ54392;FLJ54408;FLJ75127;HSP70-1;HSP70-1A;HSP70I;HSP72;HSPA1;HSPA1B ;
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
