The HSPA1A Polyclonal Antibody (PACO02105) is a valuable tool for researchers studying the heat shock 70kDa protein 1A (HSPA1A). This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the HSPA1A protein, researchers can effectively detect and analyze its expression in various cell types, making it an excellent choice for studies in cell biology, molecular biology, and cancer research.HSPA1A, also known as heat shock protein 70 (HSP70), is a chaperone protein involved in cellular stress response and protein folding. Its role in maintaining cellular homeostasis and protecting against damage from stressors such as heat, toxins, and oxidative stress makes it a key player in cell survival and disease progression.
By investigating the function and regulation of HSPA1A, researchers can gain insights into its potential as a therapeutic target for conditions such as cancer, neurodegenerative diseases, and cardiovascular disorders.The HSPA1A Polyclonal Antibody is a valuable tool for exploring the functions and molecular mechanisms of HSPA1A in various biological processes, offering researchers the opportunity to advance our understanding of cellular stress responses and disease pathogenesis.
Antibody Name:
HSPA1A Antibody
Antibody SKU:
PACO02105
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
WB:1:500-1:2000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from human HSP70 around the non-acetylation site of K246.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
HSPA1A; HSPA1; HSPA1B; Heat shock 70 kDa protein 1A/1B; Heat shock 70 kDa protein 1/2; HSP70-1/HSP70-2; HSP70.1/HSP70.2
UniProt Protein Function:
UniProt Protein Details:
NCBI Summary:
This intronless gene encodes a 70kDa heat shock protein which is a member of the heat shock protein 70 family. In conjuction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. It is also involved in the ubiquitin-proteasome pathway through interaction with the AU-rich element RNA-binding protein 1. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely related genes which encode similar proteins. [provided by RefSeq, Jul 2008]
