The HSPA14 Polyclonal Antibody (CAB7107) is a valuable tool for researchers studying the heat shock protein HSPA14, which plays a crucial role in cellular stress response and protein folding. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot analysis.HSPA14 is a member of the heat shock protein family, known for their essential functions in maintaining protein homeostasis under stressful conditions. HSPA14, in particular, has been implicated in various cellular processes, including protein quality control and chaperone activity.
The HSPA14 Polyclonal Antibody enables researchers to detect and analyze HSPA14 expression in a variety of cell types, providing insights into its role in cellular function and disease processes.Research on HSPA14 is particularly relevant in the fields of cell biology, neurodegenerative diseases, and cancer, where protein misfolding and aggregation are common features. By understanding the function of HSPA14, researchers can uncover potential therapeutic targets for diseases associated with protein misfolding and develop strategies to enhance cellular protection against stress-induced damage.
Product Name:
HSPA14 Rabbit Polyclonal Antibody
SKU:
CAB7107
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 240-509 of human HSPA14 (NP_057383.2).
Predicted to enable several functions, including ATP binding activity; misfolded protein binding activity; and unfolded protein binding activity. Predicted to be involved in several processes, including cellular response to unfolded protein; chaperone cofactor-dependent protein refolding; and protein refolding. Located in cytosol. Colocalizes with ribosome.
Purification Method:
Affinity purification
Gene ID:
51182
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using HSPA14 antibody (CAB7107) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
