The HSPA12B Polyclonal Antibody (CAB15206) is a valuable tool for researchers studying the heat shock protein HSPA12B, which plays a critical role in cellular stress response and protein folding. This antibody, raised in rabbits, is specifically designed for use in Western blot applications and is highly reactive with human samples.HSPA12B is a member of the heat shock protein family, known for their ability to protect cells from stress-induced damage and maintain protein homeostasis. As a chaperone protein, HSPA12B assists in the folding and assembly of other proteins, making it essential for cell survival under stressful conditions.
Research involving HSPA12B has implications in various fields, including cancer biology, neurodegenerative diseases, and aging. Studying the function and regulation of HSPA12B can provide valuable insights into cellular mechanisms of protein quality control and response to stress, with potential applications in drug development and therapy.Overall, the HSPA12B Polyclonal Antibody (CAB15206) offers researchers a reliable tool for detecting and analyzing HSPA12B protein expression in different cell types and tissues, advancing our understanding of cellular stress responses and protein folding mechanisms.
Product Name:
HSPA12B Rabbit Polyclonal Antibody
SKU:
CAB15206
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 552-686 of human HSPA12B (NP_443202.3).
The protein encoded by this gene contains an atypical heat shock protein 70 (Hsp70) ATPase domain and is therefore a distant member of the mammalian Hsp70 family. This gene may be involved in susceptibility to atherosclerosis. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
116835
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from LO2 cells, using HSPA12B Rabbit pAb (CAB15206) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
