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HSP90B1 P94B9AT Monoclonal Antibody [P94B9AT] (CPAB0292)

SKU:
CPAB0292
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
P94B9AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

HSP90B1 P94B9AT Monoclonal Antibody [P94B9AT] (CPAB0292)

The HSP90B1 (p94/GRP94) Polyclonal Antibody (CPAB0292) is a valuable tool for researchers studying the heat shock protein HSP90B1, also known as glucose-regulated protein 94 (GRP94). This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.HSP90B1 is an essential chaperone protein found in the endoplasmic reticulum, playing a crucial role in protein folding and quality control. It is involved in the regulation of the unfolded protein response (UPR) and has been implicated in various diseases, including cancer, autoimmune disorders, and neurodegenerative diseases.By targeting HSP90B1, researchers can gain insights into its function and its potential role in disease pathology.

The CPAB0292 antibody allows for the detection and analysis of HSP90B1 in different cell types, making it a versatile tool for studies in cell biology, immunology, and disease mechanisms.Understanding the function of HSP90B1 can provide valuable information for the development of therapeutic strategies targeting protein quality control pathways in diseases where HSP90B1 dysregulation is implicated. The CPAB0292 antibody offers researchers a reliable and specific tool to investigate HSP90B1 and its role in health and disease.

Product Name:HSP90B1 P94B9AT Antibody
Product Sku:CPAB0292
Size:5μg
Host Species:Mouse
Immunogen:Anti-human HSP9B1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human HSP9B1 protein 22-83 amino acids purified from Ecoli.
Clone:P94B9AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:HSP90B1 antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:HSP90B1 is an abundant molecular chaperone resident endoplasmic reticulum (ER) lumenal stress protein which is part of the Hsp90 family. HSP90B1 is involved in maintaining protein homeostasis in the secretory pathway as well as functioning in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells. HSP90B1 has key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90B1 protein associates with numerous cochaperones and involved in folding of newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is highly expressed in human gastric carcinoma BGC-823 cells during the whole cell cycle.
Synonyms:ECGP, GP96, TRA1, GRP94, HSP90B1, Endoplasmin, Heat shock protein 90 kDa beta member 1, 94 kDa glucose-regulated protein, gp96 homolog, Tumor rejection antigen 1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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