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HSP90B1 Monoclonal Antibody [P2H3AT] (CPAB0282)

SKU:
CPAB0282
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
P2H3AT
Applications:
WB
IF
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

HSP90B1 Monoclonal Antibody [P2H3AT] (CPAB0282)

The HSP90B1 Antibody (CPAB0282) is a polyclonal antibody designed for research involving HSP90B1, a heat shock protein that plays a crucial role in cellular homeostasis and protein folding. The antibody, raised in rabbits, is highly reactive with human samples and is validated for use in various applications including Western blot, immunohistochemistry, and flow cytometry.HSP90B1 is a chaperone protein that assists in the folding and stabilization of client proteins, helping to maintain cellular integrity and function under stress conditions. It is involved in a wide range of cellular processes, making it a key target for research in areas such as cancer biology, neurodegenerative diseases, and infectious diseases.

By utilizing the HSP90B1 Antibody, researchers can study the function and expression of HSP90B1 in different cell types and disease states, providing valuable insights into its role in cellular physiology and disease progression. This antibody is a valuable tool for understanding the complex mechanisms of protein folding and cellular stress response, offering potential opportunities for therapeutic development in the future.

Product Name:HSP90B1 Antibody
Product Sku:CPAB0282
Size:5μg
Host Species:Mouse
Immunogen:Anti-human HSP9B1 mAb, is derived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSP9B1 amino acids 676-83 purified from Ecoli.
Clone:P2H3AT.
Reactivity:Human
Applications:Western Blot, Immunofluorescence, ELISA
Purification Method:HSP90B1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2a
Background:HSP90B1 is an abundant molecular chaperone resident endoplasmic reticulum (ER) lumenal stress protein which is part of the Hsp90 family. HSP90B1 is involved in maintaining protein homeostasis in the secretory pathway as well as functioning in the intracellular trafficking of peptides from the extracellular space to the MHC class I antigen processing pathway of antigen presentation cells. HSP90B1 has key roles in signal transduction, protein folding, protein degradation, and morphologic evolution. HSP90B1 protein associates with numerous cochaperones and involved in folding of newly synthesized proteins or stabilizing and refolding denatured proteins after stress. HSP90B1 is highly expressed in human gastric carcinoma BGC-823 cells during the whole cell cycle.
Synonyms:ECGP, GP96, TRA1, GRP94, HSP90B1, Endoplasmin, Heat shock protein 90 kDa beta member 1, 94 kDa glucose-regulated protein, gp96 homolog, Tumor rejection antigen 1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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