The HSP90AA1 Polyclonal Antibody (CAB13501) is a valuable tool for researchers studying the HSP90AA1 protein, a member of the heat shock protein 90 family known for its role in protein folding and regulation of cellular processes. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.HSP90AA1 is a chaperone protein involved in the folding and stabilization of client proteins, playing a critical role in cellular homeostasis and stress response. Dysregulation of HSP90AA1 has been linked to various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.
By targeting HSP90AA1, researchers can gain insights into its function and potential therapeutic implications in these pathologies.This polyclonal antibody recognizes the HSP90AA1 protein, allowing for sensitive detection and analysis in various cell types. Its utility in immunology and cancer research makes it an essential tool for investigating the role of HSP90AA1 in disease pathogenesis and developing targeted therapies. Understanding the molecular mechanisms involving HSP90AA1 is crucial for advancing our knowledge of cellular biology and identifying novel therapeutic strategies.
Product Name:
Hsp90α Rabbit Polyclonal Antibody
SKU:
CAB13501
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 433-732 of human Hsp90α (NP_005339.3).
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3320
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Hsp90α antibody (CAB13501) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
