The HSP90 Rabbit Monoclonal Antibody (CAB5027) is a key tool for researchers studying HSP90, a molecular chaperone essential for cell survival and function. This antibody, generated from rabbit hosts, offers high specificity and sensitivity for detecting HSP90 protein in human samples, making it ideal for experiments like Western blot analysis. By binding specifically to HSP90, this antibody allows for precise detection and analysis of HSP90 levels in various cell types, aiding in research related to cell biology, cancer, and neurodegenerative diseases.
HSP90 is a critical protein involved in maintaining cellular homeostasis, folding and stabilizing client proteins, and regulating pathways essential for cell growth and survival. Dysregulation of HSP90 has been implicated in various diseases, including cancer, neurodegenerative disorders, and inflammatory conditions. Therefore, studying HSP90 using this antibody can provide valuable insights into the molecular mechanisms underlying disease pathogenesis and may inform the development of novel therapeutic strategies targeting HSP90 function.
Product Name:
Hsp90α/β Rabbit Monoclonal Antibody
SKU:
CAB5027
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 533-732 of human Hsp90α (P07900).
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
Purification Method:
Affinity purification
Gene ID:
3320/3326
Clone Number:
ARC1169
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Hsp90α/β Rabbit mAb (CAB5027) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
