The HSP90 Polyclonal Antibody (AB10001) is a valuable tool for researchers studying the heat shock protein 90 (HSP90), a molecular chaperone involved in protein folding and stability. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the HSP90 protein, this antibody enables the detection and analysis of HSP90 in various cell types, making it an ideal choice for studies in cell biology, biochemistry, and cancer research.HSP90 is a crucial player in cellular homeostasis, as it assists in the folding of client proteins and helps to maintain proteostasis.
Dysregulation of HSP90 has been linked to various diseases, including cancer, neurodegenerative disorders, and autoimmune conditions. By understanding the role of HSP90 in these diseases, researchers can develop targeted therapies that exploit the chaperone function of HSP90 or disrupt its activity for therapeutic benefit. The HSP90 Polyclonal Antibody is a valuable tool for investigating the function and regulation of HSP90 in health and disease.
Product Name:
Hsp90β Polyclonal Antibody
SKU:
CAB21799
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-300 of human Hsp90β (NP_031381.2).
This gene encodes a member of the heat shock protein 90 family; these proteins are involved in signal transduction, protein folding and degradation and morphological evolution. This gene encodes the constitutive form of the cytosolic 90 kDa heat-shock protein and is thought to play a role in gastric apoptosis and inflammation. Alternative splicing results in multiple transcript variants. Pseudogenes have been identified on multiple chromosomes.
Purification Method:
Affinity purification
Gene ID:
3326
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.09% Sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Hsp90β Rabbit pAb (CAB21799) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
