The HSP90-alpha Polyclonal Antibody is an essential tool for researchers studying the heat shock protein 90-alpha (HSP90α), a highly conserved molecular chaperone involved in protein folding, stabilization, and degradation. This antibody is raised in rabbits and exhibits high reactivity with HSP90α in human samples, making it suitable for Western blot applications.HSP90α is known to play a crucial role in various cellular functions, including cell cycle regulation, signal transduction, and protein homeostasis. Dysregulation of HSP90α has been linked to numerous diseases, such as cancer, neurodegenerative disorders, and inflammatory conditions.
By targeting HSP90α, researchers can gain valuable insights into its role in disease pathogenesis and potentially develop novel therapeutic strategies.With its specificity and sensitivity, the HSP90-alpha Polyclonal Antibody is a reliable tool for investigating the functions and mechanisms of HSP90α in a wide range of research areas, including cancer biology, neuroscience, and immunology. Its ability to detect HSP90α protein expression in different cell types makes it an indispensable reagent for in-depth studies on the molecular pathways involving HSP90α.
Product Name:
Hsp90α Rabbit Polyclonal Antibody
SKU:
CAB0365
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 433-732 of human Hsp90α (NP_005339.3).
The protein encoded by this gene is an inducible molecular chaperone that functions as a homodimer. The encoded protein aids in the proper folding of specific target proteins by use of an ATPase activity that is modulated by co-chaperones. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3320
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using Hsp90α Rabbit pAb (CAB0365) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.
