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HSP90 Alpha Monoclonal Antibody [P4F10AT] (CPAB0289)

SKU:
CPAB0289
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
P4F10AT
Applications:
WB
ELISA
IHC
€149
Frequently bought together:

Description

system_update_alt Datasheet

HSP90 Alpha Monoclonal Antibody [P4F10AT] (CPAB0289)

The HSP90 Alpha Antibody (CPAB0289) is a valuable tool for researchers studying heat shock protein 90 (HSP90) alpha, a chaperone protein involved in regulating cellular stress response and protein folding. This polyclonal antibody, produced in rabbits, specifically targets the HSP90 alpha protein and is highly reactive with human samples, making it ideal for use in Western blot applications.HSP90 alpha is a key player in cellular homeostasis and is known to interact with a wide range of client proteins involved in various cellular processes. Dysregulation of HSP90 alpha has been implicated in a number of diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases.

By targeting HSP90 alpha with this antibody, researchers can gain valuable insights into its role in these pathological conditions and develop potential therapeutic strategies.Whether investigating the role of HSP90 alpha in cancer progression, neurodegeneration, or other disease states, the HSP90 Alpha Antibody (CPAB0289) provides researchers with a reliable tool for studying this important chaperone protein and its implications for human health.

Product Name:HSP90 Alpha Antibody
Product Sku:CPAB0289
Size:5μg
Host Species:Mouse
Immunogen:Anti-human HSP9A mAb, is derived from hybridization of mouse SP2/ myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSP9A amino acids 1-732 purified from Ecoli.
Clone:P4F10AT.
Reactivity:Human
Applications:Western Blot, ELISA, Immunohistochemistry
Purification Method:HSP90A antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:HSP90 has been identified in the cytosol, nucleus and endoplasmic reticulum, and is reported to exist in many tissue types. In several tissues, including smooth muscle, HSP90 comprises up to 2% of total cellular protein. HSP90 functions as a dimer, assembled as part of heterocomplex. It possesses ATP-binding site and low ATPase activity. HSP90 is able to associate with actin filaments in certain conditions. Another important property of HSP90 is the binding of unoccupied steroid hormone receptors. HSP90 has been characterized as a molecular chaperone able to keep the target protein in a folding-competent state. It has an enhanced chaperone activity in oligomeric form at high temperatures. HSP90 function is sensitive to bivalent cations concentration.
Synonyms:HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, HSP90A, HSP90N, HSPCAL1, HSPCAL4, FLJ31884, Heat shock protein HSP 90-alpha, Renal carcinoma antigen NY-REN-38, HSP 86, HSP90AA1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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