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HSP70 Monoclonal Antibody [P4E7AT] (CPAB0288)

SKU:
CPAB0288
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG1
Clone:
P4E7AT
Applications:
WB
ELISA
IHC
€149
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Description

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HSP70 Monoclonal Antibody [P4E7AT] (CPAB0288)

The Hsp70 Polyclonal Antibody (CPAB0288) is a valuable tool for researchers studying heat shock protein 70 (Hsp70), a highly conserved chaperone protein involved in protein folding and cellular stress responses. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.Hsp70 is known to play a key role in cellular protection against stressors such as heat, toxins, and oxidative damage. Its upregulation in response to stress is a hallmark of cellular adaptation and survival mechanisms.

The Hsp70 Polyclonal Antibody specifically binds to Hsp70 protein, allowing for the detection and analysis of Hsp70 levels in various cell types.Research into the function and regulation of Hsp70 is critical for understanding its role in diseases such as cancer, neurodegenerative disorders, and cardiovascular diseases. By studying the activity of Hsp70, researchers can gain insights into potential therapeutic targets for these conditions and develop strategies to modulate cellular stress responses.

Product Name:HSP70 Antibody
Product Sku:CPAB0288
Size:5μg
Host Species:Mouse
Immunogen:Anti-human HSP7 mAb, is derived from hybridization of mouse SP2/ myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HSP7 amino acids 1-641 purified from Ecoli.
Clone:P4E7AT.
Reactivity:Human
Applications:Western Blot, ELISA, Immunohistochemistry
Purification Method:HSP70 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG1
Background:HSP70 is a human heat shock protein. HSP-70 is an important part of the cell''s machinery for protein folding, and help to protect cells from stress. In most species, there are many proteins that belong to the HSP70 family. Some of these are only expressed under stress conditions, while some are present in cells under normal growth conditions and are not heat-inducible. They can be found in different cellular compartments (nuclear, cytosolic, mitochondrial, endoplasmic reticulum, etc...).
Synonyms:Heat shock 70 kDa protein, heat shock 70kDa protein 1A, HSP70.1, HSP70-1/HSP70-2, HSPA1A, HSPA1, HSPA1B, HSP72, HSP70I, HSP70-1, FLJ54303, FLJ54370, FLJ54392, FLJ54408, FLJ75127, HSP70-1A.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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