The HSP60 Rabbit Monoclonal Antibody is a valuable tool for researchers studying heat shock protein 60 (HSP60), a chaperone protein found in mitochondria that plays a crucial role in protein folding and cellular stress responses. This antibody, generated from rabbits, is highly specific and sensitive for detecting HSP60 in human samples, making it well-suited for use in Western blot and immunohistochemistry applications.HSP60 is involved in various cellular processes, including protein folding, transportation, and quality control. Dysregulation of HSP60 expression has been linked to several diseases, including neurodegenerative disorders, cancer, and autoimmune diseases.
Therefore, understanding the expression and function of HSP60 is essential for identifying potential therapeutic targets and developing targeted treatments for these conditions.This HSP60 Rabbit Monoclonal Antibody provides researchers with a reliable tool for studying the role of HSP60 in health and disease. Its high specificity and sensitivity make it a valuable asset for investigations into the molecular mechanisms underlying HSP60 function and its potential as a therapeutic target in various pathological conditions.
Product Name:
HSP60/HSPD1 Rabbit Monoclonal Antibody
SKU:
CAB0564
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 350-450 of human HSP60/HSPD1 (P10809).
This gene encodes a member of the chaperonin family. The encoded mitochondrial protein may function as a signaling molecule in the innate immune system. This protein is essential for the folding and assembly of newly imported proteins in the mitochondria. This gene is adjacent to a related family member and the region between the 2 genes functions as a bidirectional promoter. Several pseudogenes have been associated with this gene. Two transcript variants encoding the same protein have been identified for this gene. Mutations associated with this gene cause autosomal recessive spastic paraplegia 13.
Purification Method:
Affinity purification
Gene ID:
3329
Clone Number:
ARC0260
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using HSP60/HSPD1 Rabbit mAb (CAB0564) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
