The HSP27 Rabbit Monoclonal Antibody is a valuable tool for researchers studying HSP27, a heat shock protein involved in cellular stress response and protection. This highly reactive antibody is specifically designed for use in Western blot applications and is validated for detection of the HSP27 protein in human samples.HSP27 is known to play a role in regulating cell survival, apoptosis, and cellular protection under stressful conditions. Its involvement in various cellular processes makes it a key target for research in areas such as cancer, neurodegenerative diseases, and cardiovascular disorders.
By targeting the HSP27 protein, researchers can gain insights into its function and potential therapeutic applications.The HSP27 Rabbit Monoclonal Antibody enables precise detection and analysis of HSP27 in various cell types, providing valuable information for studies in cell biology, molecular biology, and drug development. Its high specificity and sensitivity make it an essential tool for investigating the role of HSP27 in health and disease.
Product Name:
HSP27/HSPB1 Rabbit Monoclonal Antibody
SKU:
CAB11156
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-205 of human HSP27/HSPB1 (P04792).
This gene encodes a member of the small heat shock protein (HSP20) family of proteins. In response to environmental stress, the encoded protein translocates from the cytoplasm to the nucleus and functions as a molecular chaperone that promotes the correct folding of other proteins. This protein plays an important role in the differentiation of a wide variety of cell types. Expression of this gene is correlated with poor clinical outcome in multiple human cancers, and the encoded protein may promote cancer cell proliferation and metastasis, while protecting cancer cells from apoptosis. Mutations in this gene have been identified in human patients with Charcot-Marie-Tooth disease and distal hereditary motor neuropathy.
Purification Method:
Affinity purification
Gene ID:
3315
Clone Number:
ARC0531
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using HSP27/HSPB1Rabbit mAb (CAB11156) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
