The HSF2 Polyclonal Antibody (CAB2747) is a valuable tool for researchers studying the Heat Shock Factor 2 (HSF2) protein, a key regulator of cellular response to stress. This antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.HSF2 is essential for maintaining cellular homeostasis under conditions of stress, such as heat shock, oxidative stress, and DNA damage. It plays a critical role in activating the heat shock response, which helps protect cells from damage and promote survival in adverse conditions. Understanding the function and regulation of HSF2 is crucial for elucidating its role in various cellular processes, including protein folding, stress response, and cell survival.
Researchers in the fields of cell biology, molecular biology, and cancer research can benefit from using the HSF2 Polyclonal Antibody to detect and analyze HSF2 protein levels in different cell types and experimental conditions. By investigating the role of HSF2 in stress response pathways and disease mechanisms, this antibody can contribute to the development of novel therapeutic strategies targeting HSF2-related pathways in cancer, neurodegenerative disorders, and other diseases associated with cellular stress.
Product Name:
HSF2 Rabbit Polyclonal Antibody
SKU:
CAB2747
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 39-215 of human HSF2 (Q03933).
The protein encoded by this gene belongs to the HSF family of transcription factors that bind specifically to the heat-shock promoter element and activate transcription. Heat shock transcription factors activate heat-shock response genes under conditions of heat or other stresses. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3298
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates, using HSF2 antibody (CAB2747) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
