The HSF1 Polyclonal Antibody is a valuable tool for researchers studying the Heat Shock Factor 1 (HSF1) protein, a key regulator of the heat shock response in cells. This antibody, produced in rabbits, shows high specificity for human samples and is optimized for Western blot applications. By binding specifically to HSF1, researchers can accurately detect and analyze the protein in a variety of cell types, making it an essential component for studies in cell biology, stress response, and disease mechanisms.HSF1 is a transcription factor that plays a crucial role in protecting cells from stress-induced damage, such as heat shock, oxidative stress, and protein misfolding.
Dysregulation of HSF1 has been implicated in various diseases, including cancer, neurodegenerative disorders, and metabolic conditions. By understanding the function and regulation of HSF1, researchers can uncover new therapeutic targets and strategies for treating these diseases.The HSF1 Polyclonal Antibody from Assay Genie provides researchers with a reliable tool for studying the intricate functions of HSF1 and its implications in cellular stress responses and disease pathology. With its high specificity and sensitivity, this antibody is a valuable asset for any research project aiming to unravel the complexities of cellular stress and disease mechanisms.
Product Name:
HSF1 Polyclonal Antibody
SKU:
CAB21994
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 367-529 of human HSF1 (NP_005517.1).
centrosome, cytoplasm, cytosol, mitotic spindle pole, nuclear stress granule, nucleoplasm, nucleus, perinuclear region of cytoplasm, PML body
Calculated MW:
52kDa/57kDa
Observed MW:
73kDa
The product of this gene is a heat-shock transcription factor. Transcription of heat-shock genes is rapidly induced after temperature stress. Hsp90, by itself and/or associated with multichaperone complexes, is a major repressor of this gene.
Purification Method:
Affinity purification
Gene ID:
3297
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse ovary, using HSF1 Rabbit pAb (CAB21994) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
