The HSDL2 Polyclonal Antibody (PAC037106) is a valuable tool for researchers studying the HSDL2 protein, which is involved in lipid metabolism and mitochondrial function. This antibody, produced in rabbits, is highly specific to human samples and is validated for use in Western blot applications. By targeting the HSDL2 protein, this antibody enables precise detection and analysis of HSDL2 levels in various cell types, making it ideal for studies in metabolism, energy production, and mitochondrial disorders.
HSDL2, also known as hydroxysteroid dehydrogenase-like 2, is a key player in lipid metabolism pathways and is essential for maintaining cellular energy balance. Dysregulation of HSDL2 has been linked to metabolic disorders such as obesity, diabetes, and mitochondrial dysfunction. By studying the function and regulation of HSDL2, researchers can gain insights into the mechanisms underlying these metabolic diseases and potentially identify new therapeutic targets for intervention.
Western blot. All lanes: HSDL2 antibody at 3µg/ml. Lane 1: 293T whole cell lysate. Lane 2: Hela whole cell lysate. Lane 3: HepG2 whole cell lysate. Secondary. Goat polyclonal to rabbit IgG at 1/10000 dilution. Predicted band size: 46, 38 kDa. Observed band size: 46 kDa.
Immunohistochemistry of paraffin-embedded human colon cancer using PACO37106 at dilution of 1:100.
Immunohistochemistry of paraffin-embedded human prostate cancer using PACO37106 at dilution of 1:100.
Background:
Has apparently no steroid dehydrogenase activity.
Synonyms:
Hydroxysteroid dehydrogenase-like protein 2 (EC 1.-.-.-) (Short chain dehydrogenase/reductase family 13C member 1), HSDL2, C9orf99 SDR13C1
UniProt Protein Function:
HSDL2: Has apparently no steroid dehydrogenase activity. Belongs to the short-chain dehydrogenases/reductases (SDR) family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:
Protein type:EC 1.-.-.-; Mitochondrial; Oxidoreductase