HSD3B2 Rabbit Polyclonal Antibody (CAB1823)
- SKU:
- CAB1823
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Metabolism
Frequently bought together:
Description
Product Name: | HSD3B2 Rabbit Polyclonal Antibody |
SKU: | CAB1823 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-287 of human HSD3B2 (NP_000189.1). |
Sequence: | MGWS CLVT GAGG LLGQ RIVR LLVE EKEL KEIR ALDK AFRP ELRE EFSK LQNR TKLT VLEG DILD EPFL KRAC QDVS VVIH TACI IDVF GVTH RESI MNVN VKGT QLLL EACV QASV PVFI YTSS IEVA GPNS YKEI IQNG HEEE PLEN TWPT PYPY SKKL AEKA VLAA NGWN LKNG DTLY TCAL RPTY IYGE GGPF LSAS INEA LNNN GILS SVGK FSTV NPVY VGNV AWAH ILAL RALR DPKK APSV RGQF YYIS DDTP HQSY DNLN YILS KEFG LRLD SRWS LPL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:100 - 1:500 IF/ICC,1:10 - 1:100 |
Synonyms: | HSDB; HSD3B; SDR11E2; HSD3B2 |
Positive Sample: | 293T transfected with HSD3B2 |
Conjugate: | Unconjugated |
Cellular Localization: | Endoplasmic reticulum membrane, Mitochondrion membrane, Single-pass membrane protein. |
Calculated MW: | 42kDa |
Observed MW: | 42kDa |
The protein encoded by this gene is a bifunctional enzyme that catalyzes the oxidative conversion of delta(5)-ene-3-beta-hydroxy steroid, and the oxidative conversion of ketosteroids. It plays a crucial role in the biosynthesis of all classes of hormonal steroids. This gene is predominantly expressed in the adrenals and the gonads. Mutations in this gene are associated with 3-beta-hydroxysteroid dehydrogenase, type II, deficiency. Alternatively spliced transcript variants have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 3284 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3. |