The HSD17B7 Rabbit Polyclonal Antibody (CAB17157) is a powerful tool for researchers studying HSD17B7, an enzyme involved in the biosynthesis of cholesterol and steroid hormones. This antibody, generated in rabbits, has high specificity and sensitivity for detecting HSD17B7 in human samples. It has been validated for use in Western blot applications, allowing for precise detection and quantification of HSD17B7 expression in various cell types.HSD17B7 is a key enzyme in the synthesis of cholesterol and steroid hormones, playing a crucial role in lipid metabolism and hormone production.
Dysregulation of HSD17B7 has been associated with various diseases, including metabolic disorders, cardiovascular disease, and hormone-related cancers. By studying the expression and activity of HSD17B7, researchers can gain insights into the mechanisms underlying these conditions and potentially identify new therapeutic targets for intervention.
Product Name:
HSD17B7 Rabbit Polyclonal Antibody
SKU:
CAB17157
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 110-200 of human HSD17B7 (NP_057455.1).
HSD17B7 encodes an enzyme that functions both as a 17-beta-hydroxysteroid dehydrogenase (EC 1.1.1.62) in the biosynthesis of sex steroids and as a 3-ketosteroid reductase (EC 1.1.1.270) in the biosynthesis of cholesterol (Marijanovic et al., 2003 [PubMed 12829805]).
Purification Method:
Affinity purification
Gene ID:
51478
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HSD17B7 Rabbit pAb (CAB17157) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5min.
