The HSD17B12 Polyclonal Antibody (CAB17151) is a valuable tool for researchers studying the HSD17B12 protein, an enzyme involved in lipid metabolism and steroid hormone biosynthesis. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the HSD17B12 protein, researchers can detect and analyze its expression in various cell types, making it ideal for studies in metabolic diseases, hormone regulation, and cancer research.
HSD17B12, also known as type 12 17-beta-hydroxysteroid dehydrogenase, plays a crucial role in regulating the balance of hormones and lipids in the body. Dysregulation of HSD17B12 has been linked to metabolic disorders, hormone-dependent cancers, and other diseases. By studying the activity of HSD17B12, researchers can gain insights into potential therapeutic targets for these conditions and develop personalized treatment strategies for patients.
Product Name:
HSD17B12 Rabbit Polyclonal Antibody
SKU:
CAB17151
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 43-312 of human HSD17B12 (NP_057226.1).
This gene encodes a very important 17beta-hydroxysteroid dehydrogenase (17beta-HSD) that converts estrone into estradiol in ovarian tissue. This enzyme is also involved in fatty acid elongation.
Purification Method:
Affinity purification
Gene ID:
51144
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from OVCAR3 cells, using HSD17B12 Rabbit pAb (CAB17151) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
