ERAB/HSD17B10 Rabbit Polyclonal Antibody (CAB5448)
- SKU:
- CAB5448
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Epigenetics and Nuclear Signaling
Frequently bought together:
Description
Product Name: | ERAB/HSD17B10 Rabbit Polyclonal Antibody |
SKU: | CAB5448 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-261 of human ERAB/ERAB/HSD17B10 (NP_004484.1). |
Sequence: | MAAA CRSV KGLV AVIT GGAS GLGL ATAE RLVG QGAS AVLL DLPN SGGE AQAK KLGN NCVF APAD VTSE KDVQ TALA LAKG KFGR VDVA VNCA GIAV ASKT YNLK KGQT HTLE DFQR VLDV NLMG TFNV IRLV AGEM GQNE PDQG GQRG VIIN TASV AAFE GQVG QAAY SASK GGIV GMTL PIAR DLAP IGIR VMTI APGL FGTP LLTS LPEK VCNF LASQ VPFP SRLG DPAE YAHL VQAI IENP FLNG EVIR LDGA IRMQ P |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:100 IF/ICC,1:50 - 1:100 |
Synonyms: | ABAD; CAMR; ERAB; HCD2; MHBD; HADH2; MRPP2; MRX17; MRX31; SCHAD; MRXS10; SDR5C1; HSD10MD; 17b-HSD10; DUPXp11.22; ERAB/HSD17B10 |
Positive Sample: | 293T,Mouse heart,Rat kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Mitochondrion. |
Calculated MW: | 27kDa |
Observed MW: | 27kDa |
This gene encodes 3-hydroxyacyl-CoA dehydrogenase type II, a member of the short-chain dehydrogenase/reductase superfamily. The gene product is a mitochondrial protein that catalyzes the oxidation of a wide variety of fatty acids and steroids, and is a subunit of mitochondrial ribonuclease P, which is involved in tRNA maturation. The protein has been implicated in the development of Alzheimer disease, and mutations in the gene are the cause of 17beta-hydroxysteroid dehydrogenase type 10 (HSD10) deficiency. Several alternatively spliced transcript variants have been identified, but the full-length nature of only two transcript variants has been determined.
Purification Method: | Affinity purification |
Gene ID: | 3028 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |