HSCB Rabbit Polyclonal Antibody (CAB15961)
- SKU:
- CAB15961
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Signal Transduction
Frequently bought together:
Description
Product Name: | HSCB Rabbit Polyclonal Antibody |
SKU: | CAB15961 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 30-235 of human HSCB (NP_741999.3). |
Sequence: | AASQ AGSN YPRC WNCG GPWG PGRE DRFF CPQC RALQ APDP TRDY FSLM DCNR SFRV DTAK LQHR YQQL QRLV HPDF FSQR SQTE KDFS EKHS TLVN DAYK TLLA PLSR GLYL LKLH GIEI PERT DYEM DRQF LIEI MEIN EKLA EAES EAAM KEIE SIVK AKQK EFTD NVSS AFEQ DDFE EAKE ILTK MRYF SNIE EKIK LKKI PL |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | JAC1; HSC20; SIDBA5; DNAJC20; HSCB |
Positive Sample: | A-549,U-87MG,LO2,SGC-7901 |
Conjugate: | Unconjugated |
Cellular Localization: | Cytoplasm, Mitochondrion. |
Calculated MW: | 27kDa |
Observed MW: | 27kDa |
This gene encodes a DnaJ-type co-chaperone and member of the heat shock cognate B (HscB) family of proteins. The encoded protein plays a role in the synthesis of iron-sulfur clusters, protein cofactors that are involved in the redox reactions of mitochondrial electron transport and other processes. Cells in which this gene is knocked down exhibit reduced activity of iron-sulfur cluster-dependent enzymes including succinate dehydrogenase and aconitase. The encoded protein may stimulate the ATPase activity of the mitochondrial stress-70 protein. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 150274 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |