The HSC70 Rabbit Monoclonal Antibody is a powerful tool for research involving HSC70, a heat shock protein crucial for cellular processes such as protein folding and degradation. This antibody, raised in rabbits, exhibits high specificity and sensitivity towards HSC70 in human samples, making it an ideal choice for various applications including Western blotting and immunohistochemistry.HSC70, a member of the HSP70 family, plays a key role in maintaining cellular homeostasis and protection against cellular stress. It is involved in numerous biological processes, including protein folding, transport, and degradation, as well as serving as a chaperone for newly synthesized proteins.
Studies have shown that dysregulation of HSC70 is associated with several diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases, making it a valuable target for investigation and potential therapeutic intervention.By utilizing the HSC70 Rabbit Monoclonal Antibody, researchers can gain valuable insights into the function and regulation of HSC70 in various cellular contexts, paving the way for a better understanding of its role in health and disease. Its high specificity and sensitivity make it a reliable tool for furthering research in fields such as molecular biology, cell biology, and biomedical research.
Product Name:
Hsc70/HSPA8 Rabbit Monoclonal Antibody
SKU:
CAB0415
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 547-646 of human Hsc70/HSPA8 (P11142).
This gene encodes a member of the heat shock protein 70 family, which contains both heat-inducible and constitutively expressed members. This protein belongs to the latter group, which are also referred to as heat-shock cognate proteins. It functions as a chaperone, and binds to nascent polypeptides to facilitate correct folding. It also functions as an ATPase in the disassembly of clathrin-coated vesicles during transport of membrane components through the cell. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3312
Clone Number:
ARC0258
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Hsc70/HSPA8 Rabbit mAb (CAB0415) at 1：1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
