HS3ST3B1 Antibody
- SKU:
- PACO64781
- Product Type:
- Antibody
- Antibody Type:
- Polyclonal Antibody
- Reactivity:
- Human
- Applications:
- ELISA
- IHC
- Conjugation:
- Unconjugated
- Isotype:
- IgG
- Host Species:
- Rabbit
Description
HS3ST3B1 Antibody (PACO64781)
The HS3ST3B1 Polyclonal Antibody (PAC064781) is a versatile tool for researchers studying HS3ST3B1, a key enzyme involved in the sulfation of heparan sulfate proteoglycans. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for use in various applications such as Western blot and immunohistochemistry.HS3ST3B1 plays a crucial role in the modification of heparin sulfate chains, influencing various biological processes including cell signaling, cell adhesion, and extracellular matrix organization. Dysregulation of HS3ST3B1 has been linked to developmental disorders, cancer progression, and inflammatory diseases, highlighting its importance in biomedical research.
By targeting the HS3ST3B1 protein, this antibody enables precise detection and analysis in a wide range of cell types, making it an ideal tool for investigating the role of HS3ST3B1 in disease pathogenesis and identifying potential therapeutic targets. Researchers in the fields of glycobiology, cancer biology, and developmental biology will find this antibody invaluable for advancing their understanding of HS3ST3B1 function and its implications in human health.
| Product Name: | HS3ST3B1 Antibody |
| Product Code: | PACO64781 |
| Size: | 50µL |
| Target Names: | HS3ST3B1 |
| Species Reactivity: | Human |
| Host Species: | Rabbit |
| Antigen Species: | Human |
| Tested Applications: | ELISA, IHC; Recommended dilution: IHC:1:100-1:500 |
| Isotype: | IgG |
| Clone ID: | N/A |
| Conjugate: | Non-conjugated |
| Clonality: | Polyclonal |
| Antigen: | Recombinant Human Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 protein (54-390aa) |
| Form: | Liquid |
| Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Storage: | Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. |
| Aliases: | Heparan sulfate glucosamine 3-O-sulfotransferase 3B1 (EC 2.8.2.30) (Heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1) (3-OST-3B) (Heparan sulfate 3-O-sulfotransferase 3B1) (h3-OST-3B), HS3ST3B1, 3OST3B1 HS3ST3B |
| Uniprot ID: | Q9Y662 |
| Background: | Sulfotransferase that utilizes 3'-phospho-5'-adenylyl sulfate (PAPS) to catalyze the transfer of a sulfo group to an N-unsubstituted glucosamine linked to a 2-O-sulfo iduronic acid unit on heparan sulfate. Catalyzes the O-sulfation of glucosamine in IdoUA2S-GlcNS and also in IdoUA2S-GlcNH2. The substrate-specific O-sulfation generates an enzyme-modified heparan sulfate which acts as a binding receptor to Herpes simplex virus-1 (HSV-1) and permits its entry. Unlike 3-OST-1, does not convert non-anticoagulant heparan sulfate to anticoagulant heparan sulfate. |
| Research Area: | Microbiology |
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