The HRPT2/CDC73 Monoclonal Antibody is a powerful tool for researchers studying the HRPT2/CDC73 protein, which plays a crucial role in regulating gene expression and cell proliferation. This antibody, produced using advanced monoclonal antibody technology, has high specificity and sensitivity for HRPT2/CDC73 in a variety of experimental settings.The HRPT2/CDC73 protein is known to be a tumor suppressor gene, with mutations or dysregulation linked to various cancers, particularly parathyroid tumors. By targeting HRPT2/CDC73 with this monoclonal antibody, researchers can accurately detect and measure levels of the protein in cell lysates, tissue samples, and other experimental systems.
This antibody is ideal for use in techniques such as Western blotting, immunoprecipitation, and immunofluorescence, providing researchers with valuable insights into the function and regulation of HRPT2/CDC73. With its high performance and reliability, the HRPT2/CDC73 Monoclonal Antibody is a valuable tool for advancing research in cancer biology, endocrinology, and molecular oncology.
Product Name:
HRPT2 / CDC73 Monoclonal Antibody
SKU:
CAB23565
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 300-400 of human HRPT2 / CDC73 (NP_078805.3).
This gene encodes a tumor suppressor that is involved in transcriptional and post-transcriptional control pathways. The protein is a component of the the PAF protein complex, which associates with the RNA polymerase II subunit POLR2A and with a histone methyltransferase complex. This protein appears to facilitate the association of 3' mRNA processing factors with actively-transcribed chromatin. Mutations in this gene have been linked to hyperparathyroidism-jaw tumor syndrome, familial isolated hyperparathyroidism, and parathyroid carcinoma.
Purification Method:
Affinity purification
Gene ID:
79577
Clone Number:
ARC3131
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates, using HRPT2 / CDC73 Rabbit mAb (CAB23565) at 1:800 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
