The HRH2 Polyclonal Antibody (CAB14170) is a vital tool for researchers studying histamine receptors, specifically the HRH2 receptor. This antibody, produced in rabbits, is highly specific and reactive with human samples, making it ideal for use in various applications such as Western blot analysis.The HRH2 receptor is a G protein-coupled receptor that plays a key role in mediating the effects of histamine, a neurotransmitter involved in allergic responses and gastric acid secretion. By targeting this receptor, researchers can gain valuable insights into histamine signaling pathways and its impact on various physiological processes.
With its high specificity and reactivity, the HRH2 Polyclonal Antibody enables precise detection and analysis of the HRH2 receptor in different cell types, allowing for in-depth investigation into its functions and potential therapeutic implications. This antibody is a valuable tool for studies in pharmacology, immunology, and gastroenterology, providing researchers with the means to unravel the complexities of histamine receptor biology.
Product Name:
HRH2 Rabbit Polyclonal Antibody
SKU:
CAB14170
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 150-250 of human HRH2 (NP_001124527.1).
Histamine is a ubiquitous messenger molecule released from mast cells, enterochromaffin-like cells, and neurons. Its various actions are mediated by histamine receptors H1, H2, H3 and H4. Histamine receptor H2 belongs to the family 1 of G protein-coupled receptors. It is an integral membrane protein and stimulates gastric acid secretion. It also regulates gastrointestinal motility and intestinal secretion and is thought to be involved in regulating cell growth and differentiation. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
3274
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HRH2 Rabbit pAb (CAB14170) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
