HRG Rabbit Polyclonal Antibody (CAB8431)
- SKU:
- CAB8431
- Product Type:
- Antibody
- Applications:
- WB
- IHC
- Reactivity:
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Cardiovascular
Frequently bought together:
Description
Product Name: | HRG Rabbit Polyclonal Antibody |
SKU: | CAB8431 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 20-260 of human HRG (NP_000403.1). |
Sequence: | SPTD CSAV EPEA EKAL DLIN KRRR DGYL FQLL RIAD AHLD RVEN TTVY YLVL DVQE SDCS VLSR KYWN DCEP PDSR RPSE IVIG QCKV IATR HSHE SQDL RVID FNCT TSSV SSAL ANTK DSPV LIDF FEDT ERYR KQAN KALE KYKE ENDD FASF RVDR IERV ARVR GGEG TGYF VDFS VRNC PRHH FPRH PNVF GFCR ADLF YDVE ALDL ESPK NLVI NCEV FDPQ EHEN INGV PPHL G |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 |
Synonyms: | HPRG; HRGP; THPH11; HRG |
Positive Sample: | Mouse pancreas |
Conjugate: | Unconjugated |
Cellular Localization: | Secreted. |
Calculated MW: | 60kDa |
Observed MW: | 80kDa |
This histidine-rich glycoprotein contains two cystatin-like domains and is located in plasma and platelets. The physiological function has not been determined but it is known that the protein binds heme, dyes and divalent metal ions. The encoded protein also has a peptide that displays antimicrobial activity against C. albicans, E. coli, S. aureus, P. aeruginosa, and E. faecalis. It can inhibit rosette formation and interacts with heparin, thrombospondin and plasminogen. Two of the protein's effects, the inhibition of fibrinolysis and the reduction of inhibition of coagulation, indicate a potential prothrombotic effect. Mutations in this gene lead to thrombophilia due to abnormal histidine-rich glycoprotein levels.
Purification Method: | Affinity purification |
Gene ID: | 3273 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |