Hpx Antibody (PACO27441)
- SKU:
- PACO27441
- Product Type:
- Antibody
- Reactivity:
- Rat
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Hpx Antibody (PACO27441)
The HPX Antibody (PAC027441) is a valuable tool for researchers studying the haptoglobin protein, an important marker in various diseases and conditions. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to haptoglobin, the antibody enables accurate detection and analysis of this protein in different cell types, making it ideal for research in fields such as immunology and oncology.Haptoglobin is a key player in the immune response, functioning as a scavenger for free hemoglobin and exerting anti-inflammatory effects.
Its involvement in diverse physiological processes highlights its potential as a biomarker for conditions like infection, inflammation, and cancer. Research into the role of haptoglobin can provide valuable insights into disease mechanisms and facilitate the development of targeted therapies.Overall, the HPX Antibody (PAC027441) is a reliable tool for studying haptoglobin in various research areas, contributing to a better understanding of its function and implications in health and disease.
| Antibody Name: | Hpx Antibody (PACO27441) |
| Antibody SKU: | PACO27441 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Rat, Human |
| Immunogen: | Recombinant Rat Hemopexin protein (24-460AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: Hpx antibody at 4.5µg/ml + HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 52 kDa Observed band size: 52 kDa . |
| Background: | Binds heme and transports it to the liver for breakdown and iron recovery,after which the free hemopexin returns to the circulation. |
| Synonyms: | Hemopexin, Hpx |
| UniProt Protein Function: | HPX: Binds heme and transports it to the liver for breakdown and iron recovery, after which the free hemopexin returns to the circulation. Belongs to the hemopexin family. |
| UniProt Protein Details: | Protein type:Secreted; Secreted, signal peptide Chromosomal Location of Human Ortholog: 1q32 Cellular Component: cell; extracellular space Molecular Function:heme transporter activity; metal ion binding Biological Process: cellular iron ion homeostasis; heme metabolic process; heme transport; hemoglobin metabolic process; positive regulation of humoral immune response mediated by circulating immunoglobulin; positive regulation of immunoglobulin production; positive regulation of tyrosine phosphorylation of STAT protein; regulation of protein metabolic process |
| NCBI Summary: | a heme binding globulin protein [RGD, Feb 2006] |
| UniProt Code: | P20059 |
| NCBI GenInfo Identifier: | 16758014 |
| NCBI Gene ID: | 58917 |
| NCBI Accession: | NP_445770.1 |
| UniProt Secondary Accession: | P20059,Q5BKB4, |
| UniProt Related Accession: | P20059 |
| Molecular Weight: | 51,351 Da |
| NCBI Full Name: | hemopexin |
| NCBI Synonym Full Names: | hemopexin |
| NCBI Official Symbol: | Hpx  |
| NCBI Official Synonym Symbols: | Hpxn  |
| NCBI Protein Information: | hemopexin |
| UniProt Protein Name: | Hemopexin |
| Protein Family: | Hemopexin |
| UniProt Gene Name: | Hpx  |
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