The HPSE2 Polyclonal Antibody (CAB8248) is a powerful tool for researchers studying the heparanase 2 (HPSE2) protein, which plays a crucial role in the regulation of tissue development and maintenance. This antibody, produced in rabbits, exhibits high specificity and sensitivity when used with human samples, making it a reliable choice for experiments involving Western blot analysis.HPSE2 is involved in the breakdown of heparan sulfate proteoglycans, molecules that are key components of the extracellular matrix and play a crucial role in cell signaling and adhesion. Dysregulation of HPSE2 has been linked to various diseases, including cancer, inflammation, and fibrosis.
By targeting HPSE2 with this antibody, researchers can gain valuable insights into its function and potential therapeutic applications in these disease settings.With its ability to specifically detect and bind to HPSE2, the CAB8248 antibody is an essential tool for advancing research in the fields of oncology, immunology, and tissue biology. By studying the role of HPSE2 in cellular processes and disease progression, scientists can pave the way for the development of novel treatments and interventions aimed at targeting this important protein.
Product Name:
HPSE2 Rabbit Polyclonal Antibody
SKU:
CAB8248
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 42-242 of human HPSE2 (NP_068600.4).
This gene encodes a heparanase enzyme. The encoded protein is a endoglycosidase that degrades heparin sulfate proteoglycans located on the extracellular matrix and cell surface. This protein may be involved in biological processes involving remodeling of the extracellular matrix including angiogenesis and tumor progression. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
60495
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using HPSE2 Rabbit pAb (CAB8248) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
