Heparanase 1 Rabbit Polyclonal Antibody (CAB16488)
- SKU:
- CAB16488
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | Heparanase 1 Rabbit Polyclonal Antibody |
SKU: | CAB16488 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 36-275 of human Heparanase 1 (NP_001092010.1). |
Sequence: | QDVV DLDF FTQE PLHL VSPS FLSV TIDA NLAT DPRF LILL GSPK LRTL ARGL SPAY LRFG GTKT DFLI FDPK KEST FEER SYWQ SQVN QDIC KYGS IPPD VEEK LRLE WPYQ EQLL LREH YQKK FKNS TYSR SSVD VLYT FANC SGLD LIFG LNAL LRTA DLQW NSSN AQLL LDYC SSKG YNIS WELG NEPN SFLK KADI FING SQLG EDFI QLHK LLRK STFK NAKL YGPD VGQP RRKT |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | HPA; HPA1; HPR1; HSE1; HPSE1; Heparanase 1 |
Positive Sample: | Jurkat,BxPC-3,A-431,mouse spleen,mouse lung,rat spleen,rat lung |
Conjugate: | Unconjugated |
Cellular Localization: | Lysosome membrane, Nucleus, Peripheral membrane protein, Secreted. |
Calculated MW: | 61kDa |
Observed MW: | 50kDa/65kDa |
Heparan sulfate proteoglycans are major components of the basement membrane and extracellular matrix. The protein encoded by this gene is an enzyme that cleaves heparan sulfate proteoglycans to permit cell movement through remodeling of the extracellular matrix. In addition, this cleavage can release bioactive molecules from the extracellular matrix. Several transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 10855 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |