HPS4 Rabbit Polyclonal Antibody (CAB16157)
- SKU:
- CAB16157
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | HPS4 Rabbit Polyclonal Antibody |
SKU: | CAB16157 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 387-708 of human HPS4 (NP_071364.4). |
Sequence: | FAFL HVPV PDGR APYC KASL SASS SLEP TPPE DTAI SSLR PPSA PEML TQHG AQEQ LEDH PGHS SQAP IPRA DPLP RRTR RPLL LPRL DPGQ RGNK LPTG EQGL DEDV DGVC ESHA APGL ECSS GSAN CQGA GPSA DGIS SRLT PAES CMGL VRMN LYTH CVKG LVLS LLAE EPLL GDSA AIEE VYHS SLAS LNGL EVHL KETL PRDE AAST SSTY NFTH YDRI QSLL MANL PQVA TPQD RRFL QAVS LMHS EFAQ LPAL YEMT VRNA STAV YACC NPIQ ETYF QQLA PAAR SSGF PNPQ DGAF SLSG KAKQ KLLK HGVN LL |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | LE; BLOC3S2; HPS4 |
Positive Sample: | U-87MG |
Conjugate: | Unconjugated |
Cellular Localization: | cytoplasm, cytoplasmic vesicle, cytosol, lysosome, melanosome |
Calculated MW: | 77kDa |
Observed MW: | 90kDa |
This gene encodes a protein component of biogenesis of lysosome-related organelles complexes (BLOC). BLOC complexes are important for the formation of endosomal-lysosomal organelles such as melanosomes and platelet dense granules. Mutations in this gene result in subtype 4 of Hermansky-Pudlak syndrome, a form of albinism. Alternative splicing results in multiple transcript variants.
Purification Method: | Affinity purification |
Gene ID: | 89781 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |