null

HPRT PAT1D9AT Monoclonal Antibody [PAT1D9AT] (CPAB0271)

SKU:
CPAB0271
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
PAT1D9AT
Applications:
WB
ELISA
FC
€149
Frequently bought together:

Description

system_update_alt Datasheet

HPRT PAT1D9AT Monoclonal Antibody [PAT1D9AT] (CPAB0271)

The HPRT Polyclonal Antibody (CPAB0271) is a specialized research tool designed for the study of HPRT, an enzyme involved in the salvage pathway of purine biosynthesis. This antibody, produced in rabbits, exhibits high reactivity with human samples and is well-suited for use in Western blot applications. By specifically binding to the HPRT protein, researchers can detect and analyze its expression in various cell types, making it an invaluable tool for investigations in molecular biology and metabolic research.HPRT plays a crucial role in the synthesis of purine nucleotides, essential components of DNA and RNA. Dysregulation of HPRT activity has been linked to various genetic disorders, making it a target of interest for studies on purine metabolism and genetic diseases.

The HPRT Polyclonal Antibody aids in the exploration of HPRT's function and regulation, providing insights into its involvement in metabolic pathways and potential therapeutic applications in the treatment of related disorders.Overall, the HPRT Polyclonal Antibody offers researchers a reliable and specific tool for studying HPRT expression and function, paving the way for advancements in understanding purine metabolism and associated genetic conditions.

Product Name:HPRT PAT1D9AT Antibody
Product Sku:CPAB0271
Size:5μg
Host Species:Mouse
Immunogen:Anti-human HPRT mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human HPRT amino acids 1-218 purified from Ecoli.
Clone:PAT1D9AT.
Reactivity:Human
Applications:Western Blot, ELISA, Flow Cytometry
Purification Method:HPRT antibody was purified from mouse ascitic fluids by protein-A affinity chromatography.
Isotype:IgG2b
Background:HPRT1 has a main part in the generation of purine nucleotides through the purine salvage pathway. HPRT1 primarily functions to salvage purines from degraded DNA to renewed purine synthesis. Therefore, it performs as a catalyst in the reaction between guanine and phosphoribosyl pyrophosphate to form GMP.
Synonyms:Hypoxanthine-Guanine Phosphoribosyltransferase , EC 2.4.2.8, HGPRT, HGPRTase, HPRT, HPRT1.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

Related Products