The HPCAL4 Polyclonal Antibody (CAB15448) is a valuable tool for researchers studying HPCAL4, a neuronal calcium-binding protein involved in calcium signaling pathways. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.HPCAL4 is known to play a role in various cellular processes, including neurotransmitter release, synaptic plasticity, and neuronal development. Its involvement in calcium signaling makes it a key player in neuronal function and has implications for neurological disorders such as Alzheimer's disease and Parkinson's disease.
By targeting the HPCAL4 protein, researchers can gain insights into its functions and mechanisms in different cell types, providing valuable information for studies in neuroscience and neurodegenerative diseases. The HPCAL4 Polyclonal Antibody is an essential tool for investigating the role of HPCAL4 in normal physiological processes and disease states, ultimately contributing to the development of new therapeutic strategies.
Product Name:
HPCAL4 Rabbit Polyclonal Antibody
SKU:
CAB15448
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-191 of human HPCAL4 (NP_057341.1).
U-251MG,293T,LO2,Mouse brain,Mouse kidney,Mouse liver,Mouse testis,Rat brian
Conjugate:
Unconjugated
Calculated MW:
22kDa
Observed MW:
22kDa
The protein encoded by this gene is highly similar to human hippocalcin protein and hippocalcin like-1 protein. It also has similarity to rat neural visinin-like Ca2+-binding protein-type 1 and 2 proteins. This encoded protein may be involved in the calcium-dependent regulation of rhodopsin phosphorylation. The transcript of this gene has multiple polyadenylation sites. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
51440
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HPCAL4 Rabbit pAb (CAB15448) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
