The HOXD3 Polyclonal Antibody (CAB15279) is a valuable tool for researchers studying HOXD3, a transcription factor involved in the development and patterning of tissues during embryogenesis. This antibody, produced in rabbits, shows high specificity and sensitivity in detecting HOXD3 protein in human samples, making it ideal for use in Western blot and immunohistochemistry applications.HOXD3 plays a crucial role in the regulation of gene expression and cellular differentiation, making it a key player in developmental processes and tissue morphogenesis. Dysregulation of HOXD3 has been linked to various diseases, including cancer and developmental disorders, highlighting the importance of studying its function and mechanisms of action.
By using the HOXD3 Polyclonal Antibody (CAB15279), researchers can accurately detect and analyze HOXD3 expression in different cell types and tissues, providing valuable insights into its role in normal development and disease pathology. This antibody is a valuable tool for studies in developmental biology, cancer research, and regenerative medicine, offering new avenues for understanding HOXD3 function and its potential as a therapeutic target.
Product Name:
HOXD3 Rabbit Polyclonal Antibody
SKU:
CAB15279
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 263-432 of human HOXD3 (NP_008829.3).
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located at 2q31-2q37 chromosome regions. Deletions that removed the entire HOXD gene cluster or 5' end of this cluster have been associated with severe limb and genital abnormalities. The protein encoded by this gene may play a role in the regulation of cell adhesion processes.
Purification Method:
Affinity purification
Gene ID:
3232
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from U-251MG cells, using HOXD3 Rabbit pAb (CAB15279) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
