The HOXD10 Monoclonal Antibody is a cutting-edge research tool designed for scientists studying the HOXD10 protein, a key player in developmental biology and cancer research. This antibody, produced using advanced technology, specifically targets the HOXD10 protein and is highly specific for human samples. HOXD10 is a critical transcription factor that regulates gene expression and plays a vital role in the development of various tissues and organs. Dysregulation of HOXD10 has been linked to cancer progression and metastasis, making it a promising target for cancer therapy research.
With its high specificity and sensitivity, the HOXD10 Monoclonal Antibody is ideal for techniques such as Western blotting, immunofluorescence, and immunohistochemistry, allowing researchers to accurately detect and analyze the expression of HOXD10 in different cell types and tissues. By using this antibody, scientists can gain valuable insights into the function of HOXD10 and its implications in cancer biology, ultimately leading to the development of novel therapies for the treatment of cancer and other diseases.
Product Name:
HOXD10 Monoclonal Antibody
SKU:
CAB23992
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant Protein corresponding to a sequence within amino acids 1-150 of human HOXD10 (NP_002139.2).
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and limb development. Mutations in this gene have been associated with Wilm's tumor and congenital vertical talus (also known as "rocker-bottom foot" deformity or congenital convex pes valgus) and/or a foot deformity resembling that seen in Charcot-Marie-Tooth disease.
Purification Method:
Affinity purification
Gene ID:
3236
Clone Number:
ARC62112
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of Mouse kidney, using HOXD10 Rabbit mAb (CAB23992) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25ug per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
