The HOXC4 Polyclonal Antibody (CAB8986) is a valuable tool for researchers studying the HOXC4 protein, a member of the homeobox gene family involved in regulating development and differentiation. This antibody, produced in rabbits, exhibits high reactivity with human samples and is specifically validated for use in Western blot applications.HOXC4 is known to play a key role in embryonic development and cell differentiation, making it a crucial target for investigations in developmental biology and cancer research. By binding to the HOXC4 protein, this antibody enables precise detection and analysis in a variety of cell types, providing valuable insight into the functions and mechanisms underlying HOXC4's regulatory roles.
The HOXC4 Polyclonal Antibody is an essential tool for researchers seeking to enhance their understanding of HOXC4's functions and explore its potential implications in various biological processes. Its reliability and specificity make it an ideal choice for studies aimed at uncovering the intricate pathways and interactions involving HOXC4, paving the way for advancements in developmental biology and targeted therapies for cancer and other diseases.
Product Name:
HOXC4 Rabbit Polyclonal Antibody
SKU:
CAB8986
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-130 of human HOXC4 (NP_055435.2).
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons.
Purification Method:
Affinity purification
Gene ID:
3221
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HOXC4 Rabbit pAb (CAB8986) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 300s.
