Description
HOXC4 Antibody (CAB13856)
The HOXC4 Antibody (CAB13856) is a high-quality antibody developed for reliable detection and analysis of target proteins. This antibody, produced in rabbits, exhibits high specificity and sensitivity for detecting human HOXC4 in various research applications, including Western blotting.HOXC4 is known to regulate gene expression and cell differentiation in multiple tissues, making it a key player in embryonic development and adult tissue homeostasis. Dysregulation of HOXC4 has been linked to various diseases, including cancer, where it can act as an oncogene or tumor suppressor depending on the context.
This antibody is validated for use in WB, ELISA applications and has demonstrated reactivity against Mouse, Rat samples.
| Product Name: | HOXC4 Antibody |
| SKU: | CAB13856 |
| Size: | 20μL, 100μL |
| Reactivity: | Mouse, Rat |
| Conjugate: | Unconjugated |
| Immunogen: | Recombinant protein (or fragment).This information is considered to be commercially sensitive. | ||||
| Sequence: | PEHS PEYY GRTR ESGF QHHH QELY PPPP PRPS YPER QYSC TSLQ GPGN SRGH GPAQ AGHH HPEK SQSL CEPA PLSG ASAS PSPA PPAC SQPA PDHP SSAA S | ||||
| Tested Applications: | WB ELISA | ||||
| Recommended Dilution: |
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| Synonyms: | HOX3, cp19, HOX3E, HOXC4 |
| Positive Sample: | Mouse liver, Rat liver |
| Cellular Localization: | Nucleus. |
| Calculated MW: | 30kDa |
| Observed MW: | 30kDa |
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, which are located on different chromosomes and consist of 9 to 11 genes arranged in tandem. This gene, HOXC4, is one of several homeobox HOXC genes located in a cluster on chromosome 12. Three genes, HOXC5, HOXC4 and HOXC6, share a 5' non-coding exon. Transcripts may include the shared exon spliced to the gene-specific exons, or they may include only the gene-specific exons. Two alternatively spliced variants that encode the same protein have been described for HOXC4. Transcript variant one includes the shared exon, and transcript variant two includes only gene-specific exons.
| Purification Method | Affinity purification |
| Gene ID | 3221 |
| RRID | AB_2760707 |
| Buffer Information | Store at -20℃. Avoid freeze / thaw cycles. Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |
 | Western blot analysis of various lysates using HOXC4 Rabbit pAb (CAB13856) at 1:3000 dilution. Secondary antibody: HRP-conjugated Goat anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution. Lysates/proteins: 25μg per lane. Blocking buffer: 3% nonfat dry milk in TBST. Detection: ECL Enhanced Kit (AbGn00021). Exposure time: 90s. |
