The HOXB9 Polyclonal Antibody (CAB10222) is a crucial tool for researchers studying the HOXB9 protein, a transcription factor involved in various biological processes, including embryonic development and cell differentiation. This antibody, generated in rabbits, exhibits high specificity and sensitivity towards human samples, making it ideal for use in Western blotting and immunofluorescence applications.HOXB9, a member of the HOX gene family, plays a key role in regulating gene expression patterns that control cell fate determination and tissue patterning.
Dysregulation of HOXB9 has been implicated in various diseases, such as cancer, making it a promising target for therapeutic interventions. By using the HOXB9 Polyclonal Antibody, researchers can gain valuable insights into the functions of HOXB9 in different cellular contexts, advancing our understanding of its role in health and disease.
Product Name:
HOXB9 Rabbit Polyclonal Antibody
SKU:
CAB10222
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-80 of human HOXB9 (NP_076922.1).
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of leukemia, prostate cancer and lung cancer.
Purification Method:
Affinity purification
Gene ID:
3219
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse kidney, using HOXB9 Rabbit pAb (CAB10222) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 30s.