The HOXB7 Polyclonal Antibody (CAB6925) is a vital tool for researchers investigating the HOXB7 gene, a critical regulator of cellular processes such as cell proliferation, differentiation, and migration. This antibody, produced through rabbit immunization, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for studies utilizing Western blot techniques.HOXB7, a member of the HOX family of transcription factors, has been implicated in various biological processes, including embryonic development and cancer progression. Its dysregulation has been linked to tumorigenesis and metastasis in several cancer types, highlighting its potential as a therapeutic target for cancer treatment.
By enabling the detection and quantification of HOXB7 expression in different cell types, this antibody facilitates in-depth analyses crucial for understanding the mechanisms underlying these processes.Researchers in the fields of oncology, developmental biology, and molecular biology will benefit from the utility of the HOXB7 Polyclonal Antibody (CAB6925) in elucidating the roles of HOXB7 in normal and disease states. Its reliability and specificity make it a valuable asset for advancing knowledge in these areas and potentially identifying new avenues for targeted therapeutic interventions.
Product Name:
HOXB7 Rabbit Polyclonal Antibody
SKU:
CAB6925
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-120 of human HOXB7 (NP_004493.3).
This gene is a member of the Antp homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded nuclear protein functions as a sequence-specific transcription factor that is involved in cell proliferation and differentiation. Increased expression of this gene is associated with some cases of melanoma and ovarian carcinoma.
Purification Method:
Affinity purification
Gene ID:
3217
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse kidney, using HOXB7 antibody (CAB6925) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 60s.
