The HOXB5 Polyclonal Antibody (CAB8123) is a valuable tool for researchers studying the HOXB5 protein, a member of the homeobox family of transcription factors involved in development and cell differentiation. This antibody, raised in rabbits, has high specificity for human samples and has been validated for use in Western blot applications. By binding to the HOXB5 protein, this antibody allows for the detection and analysis of HOXB5 expression in various cell types, making it ideal for studies in developmental biology and cancer research.
HOXB5 plays a crucial role in the regulation of gene expression and cell fate determination during embryonic development. Its dysregulation has been implicated in various diseases, including cancer and developmental disorders. Understanding the function of HOXB5 is essential for uncovering its role in disease progression and potential therapeutic targets. The HOXB5 Polyclonal Antibody provides researchers with a reliable tool for investigating the function of HOXB5 in various biological processes.
Product Name:
HOXB5 Rabbit Polyclonal Antibody
SKU:
CAB8123
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 170-269 of human HOXB5 (NP_002138.1).
This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in lung and gut development. Increased expression of this gene is associated with a distinct biologic subset of acute myeloid leukemia (AML) and the occurrence of bronchopulmonary sequestration (BPS) and congenital cystic adenomatoid malformation (CCAM) tissue.
Purification Method:
Affinity purification
Gene ID:
3215
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of Rat lung, using HOXB5 antibody (CAB8123) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 0.2s.
