The HOXB13 Polyclonal Antibody (CAB15779) is a vital tool for researchers investigating the HOXB13 gene, which plays a critical role in prostate cancer development and progression. This antibody, derived from rabbit serum, exhibits high specificity and sensitivity towards human samples, making it an ideal choice for use in various research applications, including Western blot and immunohistochemistry.HOXB13 is a transcription factor that is aberrantly expressed in prostate cancer cells, contributing to the aggressive nature of this disease. By targeting HOXB13 with this polyclonal antibody, researchers can accurately detect and study the expression of this gene in different cell types and tissue samples, providing valuable insights into the molecular mechanisms underlying prostate cancer.
Moreover, the HOXB13 Polyclonal Antibody is an essential tool for investigating potential therapeutic targets for prostate cancer treatment. By understanding the role of HOXB13 in tumor development and progression, researchers can identify novel strategies for personalized medicine and the development of targeted therapies for prostate cancer patients.
Product Name:
HOXB13 Rabbit Polyclonal Antibody
SKU:
CAB15779
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 50-150 of human HOXB13 (NP_006352.2).
DU145,HeLa,HT-29,Mouse small intestine,Rat small intestine
Conjugate:
Unconjugated
Cellular Localization:
Nucleus.
Calculated MW:
31kDa
Observed MW:
27kDa
This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region.
Purification Method:
Affinity purification
Gene ID:
10481
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using HOXB13 Rabbit pAb (CAB15779) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
