The HOXB1 Polyclonal Antibody (CAB6619) is a vital tool for researchers studying the HOXB1 protein, a transcription factor essential for proper embryonic development. This antibody, produced in rabbits, shows high reactivity with human samples and has been validated for use in Western blot applications. By binding specifically to the HOXB1 protein, this antibody allows for the precise detection and analysis of HOXB1 expression in a variety of cell types.HOXB1 is a crucial regulator of gene expression during early development, playing a key role in specifying the identity of cells in the developing embryo.
Dysregulation of HOXB1 has been implicated in a range of developmental disorders and diseases, making it an important focus of study in fields such as developmental biology and regenerative medicine. Understanding the function of HOXB1 is essential for uncovering its role in these processes and potentially developing new therapies for related conditions.
Product Name:
HOXB1 Rabbit Polyclonal Antibody
SKU:
CAB6619
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 35-180 of human HOXB1 (NP_002135.2).
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17.
Purification Method:
Affinity purification
Gene ID:
3211
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of Mouse heart, using HOXB1 antibody (CAB6619) at 1:4000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
