The HOXB1 / HOXA1 / HOXD1 Polyclonal Antibody (PACO04062) is a valuable tool for researchers studying the HOXB1, HOXA1, and HOXD1 genes, which play crucial roles in development and body pattern formation. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for use in Western blot applications.HOXB1, HOXA1, and HOXD1 are homeobox genes that are essential for the formation of structures in the body during embryonic development. Aberrant expression or mutations in these genes have been linked to developmental disorders and diseases. By using this antibody, researchers can detect and analyze the expression levels of HOXB1, HOXA1, and HOXD1 proteins in various cell types, providing insights into their functions and potential roles in diseases.
With its high specificity and reactivity, the HOXB1 / HOXA1 / HOXD1 Polyclonal Antibody is a valuable tool for researchers in the fields of developmental biology, genetics, and molecular biology. By elucidating the roles of HOXB1, HOXA1, and HOXD1 in development and disease, this antibody can contribute to the advancement of knowledge and potential therapeutic strategies.
Antibody Name:
HOXB1/HOXA1/HOXD1 Antibody
Antibody SKU:
PACO04062
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IHC
Recommended Dilutions:
IHC:1:100-1:300
Species Reactivity:
Human, Mouse
Immunogen:
synthesized peptide derived from the C-terminal region of human Hox-A1/B1/D1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
HOXB1; HOX2I; Homeobox protein Hox-B1; Homeobox protein Hox-2I; HOXA1; HOX1F; Homeobox protein Hox-A1; Homeobox protein Hox-1F; HOXD1; HOX4; HOX4G; Homeobox protein Hox-D1; Homeobox protein Hox-GG
UniProt Protein Function:
Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Acts on the anterior body structures.
NCBI Summary:
This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXB genes located in a cluster on chromosome 17. [provided by RefSeq, Jul 2008]
