The HOXA9 Polyclonal Antibody (CAB1908) is a valuable tool for researchers studying the HOXA9 gene, which plays a crucial role in development and differentiation processes. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the HOXA9 protein, this antibody enables researchers to detect and analyze HOXA9 expression in a variety of cell types.HOXA9 is a member of the HOX gene family, which are key regulators of embryonic development and cell differentiation. Aberrant expression of HOXA9 has been linked to various diseases, including leukemia and other cancers, making it a key target for research in oncology and stem cell biology.
Understanding the role of HOXA9 in these diseases can provide valuable insights for developing targeted therapies and treatments.Overall, the HOXA9 Polyclonal Antibody is an essential tool for researchers investigating the function and regulation of the HOXA9 gene in both normal development and disease processes. Its high specificity and sensitivity make it an ideal choice for immunology, cancer research, and developmental biology studies.
Product Name:
HOXA9 Rabbit Polyclonal Antibody
SKU:
CAB1908
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-190 of human HOXA9 (NP_689952.1).
In vertebrates, the genes encoding the class of transcription factors called homeobox genes are found in clusters named A, B, C, and D on four separate chromosomes. Expression of these proteins is spatially and temporally regulated during embryonic development. This gene is part of the A cluster on chromosome 7 and encodes a DNA-binding transcription factor which may regulate gene expression, morphogenesis, and differentiation. This gene is highly similar to the abdominal-B (Abd-B) gene of Drosophila. A specific translocation event which causes a fusion between this gene and the NUP98 gene has been associated with myeloid leukemogenesis. Read-through transcription exists between this gene and the upstream homeobox A10 (HOXA10) gene.
Purification Method:
Affinity purification
Gene ID:
3205
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using HOXA9 Rabbit pAb (CAB1908) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
